Ice’s Personal Website

About me

I am an Engineering Excellence Postdoctoral Fellow at the Massachusetts Institute of Technology, working with James J. Collins at the Institute for Medical Engineering and Science. My research focuses on antimicrobial resistance and engineered living therapeutics—using synthetic biology, microbial engineering, and genetic circuits to design living systems that can address human-health challenges.

Current research

  • Engineered living therapeutics: designing microorganisms that can sense and respond to disease-relevant signals.
  • Antimicrobial resistance: developing genetic approaches to target antibiotic-resistance genes in complex microbial communities.
  • Microbial CRISPR and genetic circuits: creating portable tools for programming diverse bacterial species, with applications in metabolic engineering and microbiome engineering.

I earned my Ph.D. in Molecular Engineering and Sciences at the University of Washington, where I worked with James Carothers and Jesse Zalatan. During my doctoral research, I developed portable CRISPR-based gene-regulation technologies for programming diverse bacterial species, with applications in metabolic engineering and genetic circuitry.

At MIT, I am exploring how engineered microbes and microbial communities can be used to combat antimicrobial resistance. I am particularly interested in developing genetic approaches that target antibiotic-resistance genes in complex microbiomes and in connecting these approaches with AI-assisted antibiotic discovery.

Selected research

Recent Updates

June 2, 2026 · Publication
CRISPRi-assisted E. coli strains increase success rate of burdensome construct cloning
A bioRxiv preprint describing CRISPRi cloning strains that suppress burdensome genetic constructs during assembly.
April 17, 2026 · Publication
Conjugation-based genome engineering enables rapid prototyping and bioproduction in non-model bacteria
A bioRxiv preprint describing a broad-host-range platform for iterative genome engineering in non-model bacteria.
April 8, 2024 · Blog
EBRC In Translation
A podcast created by members of the EBRC Student and Postdoc Association to explore engineering biology beyond the laboratory.
November 3, 2023 · Talk
Invited to ACS BRIDGE Career Kickstarter Workshop
ACS BRIDGE hosted a Career Kick-Starter workshop for professional development.Ice was invited to the workshop to foster DEI initiave across chemical sciences.With great experience from the CKS workshop, Ice is bringing the workshop to UW with sponsorship from UW Department of Chemistry!!!
November 1, 2023 · Teaching
SynBio4ALL Intro Course 2023
Ice co-founded the educational initiative for African students focusing on Synthetic Biology.He was in charge of the asynchronous learning using his experience from being a youtuber!!!More information can be found at the SynBio4ALL websiteIce taught Lecture 5 focusing on Laboratory Techniques in Synthetic Biologyand also co-taught Lecture 6 with Heidi in the 2nd part focusing on CRISPR Technologies
September 13, 2023 · Teaching
EBRC Panel 2023
Together with EBRC-SPA team, especially Ross Jones, Ice co-lead the panel series focusing on “Introduction to Graduate School in Engineering Biology” for Engineering Biology students.The recordings of our panels were available on EBRC’s youtube channel.

Background

I was born and raised in Thailand and received my B.Sc. and M.Sc. degrees in Organic Chemistry from Mahidol University. I later joined the founding team of the School of Biomolecular Sciences and Engineering at VISTEC, where I worked on enzyme biocatalysis before moving into synthetic biology.

Outside the lab, I enjoy hiking, surfing, climbing, Muay Thai, and cooking Thai food. Ice also enjoy music, arts, and many other entertainment media. If there’s any fun activities in town ongoing, Ice may drop by after finishing the lab task.

Ice's academic and research journey from Thailand to Seattle and Boston

Community engagement

I am actively involved in building engineering-biology communities in the United States, Thailand, and internationally. I previously served as a board member of the Engineering Biology Research Consortium (EBRC) Student and Postdoc Association (SPA), helping foster connections across the synthetic-biology community.

Through connections formed at EBRC, I helped co-found SynBio4ALL, an initiative created to expand access to synthetic-biology education for African students. I have also supported the development of Thailand’s synthetic-biology community through teaching, public communication, and the Thailand Synthetic Biology Consortium.

I have deep interest in politics and policy since I was capable of reading. See Blogs section to explore more non-STEM content.

I also contribute to How To Grow (Almost) Anything, a global synthetic-biology course based at MIT and Harvard. As a member of the teaching staff, I support laboratory and recitation instruction in areas including DNA assembly, cell-free systems, and CRISPR-based metabolic engineering.

I believe that education is always evolving and at the age of AI with many paradigm shifts, we need to adjust the curriculum beyond conventional route. I discussed several ideas in the Curriculum Framework commissioned by UNESCO to build a guideline for Low- and Middle-Income Countries.

Engineering Biology Research Consortium SynBio4ALL Thailand Synthetic Biology Consortium