How many plasmids can bacteria carry? A synthetic biology perspective
Published in Open Biology, 2025
Abstract
This perspective examines how many unique plasmids a bacterium can maintain, synthesizing evidence from natural and engineered multi-plasmid systems. It discusses compatible replicons, selectable markers, copy-number constraints, stability, and the opportunities that multi-plasmid systems create for synthetic biology and metabolic engineering.
Recommended citation: Kiattisewee C. (2025). "How many plasmids can bacteria carry? A synthetic biology perspective." Open Biology. 15(7):240378. DOI: 10.1098/rsob.240378. PMID: 40730232. https://doi.org/10.1098/rsob.240378